Osteoarthritis – Knee Pain

Genicular Artery Embolization (GAE)

A minimally invasive procedure to help reduce knee pain from osteoarthritis—without major surgery.

Not an emergency service. If you are experiencing a medical emergency, call 911.

What Is Knee Osteoarthritis?

Osteoarthritis (OA) of the knee is a degenerative joint condition marked by inflammation, cartilage wear, and bony changes. It often causes persistent pain, stiffness, swelling, and reduced mobility that can limit daily activities.

Understanding Genicular Artery Embolization (GAE)

Genicular Artery Embolization (GAE) is a minimally invasive, outpatient procedure that targets abnormal blood vessels feeding inflammation in the knee. Using a tiny catheter under imaging guidance, our specialist advances into the genicular arteries and delivers microscopic particles to reduce abnormal blood flow, calm inflammation, and relieve pain.

Procedure at a Glance

Setting: Outpatient; local anesthesia with light sedation.
Time: Typically, 1–2 hours.
Aftercare: Bandage at the entry site; most patients go home the same day.
Recovery: Light activities in 1–2 days; soreness or bruising is usually mild and temporary.
Relief Timeline: Many patients notice improvement within 1–2 weeks, with benefits building over time.

Who Is a Good Candidate?

GAE may be appropriate if you:

  • Have moderate–severe knee OA confirmed by imaging.
  • Continue to have pain despite medications, injections, or physical therapy.
  • Prefer to avoid or delay knee replacement surgery—or are not a candidate for surgery.

GAE may also be considered for select patients with recurrent post-surgical knee bleeding (hemarthrosis). Your provider will review your history, imaging, and prior treatments to determine fit.

Benefits of GAE

  • Minimally invasive: No large incisions or general anesthesia.
  • Quick recovery: Back to light activity in a day or two.
  • Meaningful relief: Reduced pain and improved function.
  • Lower medication reliance: Many patients decrease use of pain medicines.

Risks & Safety

GAE is generally safe. Temporary bruising, mild swelling, or skin discoloration can occur. More serious complications are rare but can include non-target embolization or contrast reactions. Your provider will review individualized risks and benefits.

Evidence & Outcomes

Published clinical studies report significant pain reduction and functional improvement for many patients following GAE, with relief often sustained for 1–3 years. Outcomes vary based on OA severity, overall health, and adherence to post-procedure guidance.

Why Choose North Mississippi Vascular Care?

We offer GAE in a comfortable, state-of-the-art outpatient setting, delivered by experienced specialists who focus on safety, outcomes, and patient experience. Our team collaborates with you and your primary/orthopedic providers to personalize care.

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Frequently Asked Questions (FAQs)

What is GAE in simple terms?

A catheter-based procedure that reduces abnormal knee blood flow driving inflammation, easing OA pain.

How is it different from knee replacement?

GAE is non-surgical and minimally invasive; no joint removal or replacement and typically same-day discharge.

Who is a good candidate?

Patients with moderate–severe OA who haven’t improved with conservative care or who wish to avoid/delay surgery.

When will I feel better?

Many patients notice improvement within 1–2 weeks, with continued gains over several months.

How long will relief last?

Studies show relief can last 1–3 years for many patients; results vary.

Is the procedure painful?

Discomfort is typically minimal. Some soreness or bruising at the entry site may occur and usually resolves quickly.

What is recovery like?

Most return to light activities in 1–2 days and resume normal routines shortly thereafter.

Are there risks?

Yes—mostly minor and temporary; serious complications are uncommon. Your provider will discuss specifics.

Will GAE cure osteoarthritis?

GAE does not regrow cartilage or cure OA, but it can significantly reduce pain and improve function/quality of life.

How do I find out if I qualify?

Schedule a consultation. We’ll review your history, imaging, and prior treatments to determine if GAE is right for you.

Call to Action

If knee pain is limiting your life, you may not need to wait for surgery. Ask about Genicular Artery Embolization at North Mississippi Vascular Care.

This page provides general information and is not a substitute for professional medical advice. Always consult your healthcare provider for personalized guidance.